3 citations · 6 across the 14 of their papers we have counts for
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q-bio.BM2022★ 1 cited
AlphaFold2 can predict single-mutation effects
John M. McBride, Konstantin Polev, Amirbek Abdirasulov +3
AlphaFold2 (AF) is a promising tool, but is it accurate enough to predict single mutation effects? Here, we report that the localized structural deformation between protein pairs d…
q-bio.BM2022
General theory of specific binding: insights from a genetic-mechano-chemical protein model
John M McBride, Jean-Pierre Eckmann, Tsvi Tlusty
Proteins need to selectively interact with specific targets among a multitude of similar molecules in the cell. But despite a firm physical understanding of binding interactions, w…