17 citations · 17 across the 2 of their papers we have counts for
2 papers
stat.ME2020
A modified weighted log-rank test for confirmatory trials with a high proportion of treatment switching
José L. Jiménez, Julia Niewczas, Alexander Bore +1
In confirmatory cancer clinical trials, overall survival (OS) is normally a primary endpoint in the intention-to-treat (ITT) analysis under regulatory standards. After the tumor pr…
stat.ME2019★ 17 cited
Quantifying treatment differences in confirmatory trials under non-proportional hazards
José L. Jiménez
Proportional hazards are a common assumption when designing confirmatory clinical trials in oncology. With the emergence of immunotherapy and novel targeted therapies, departure fr…