250 citations · 269 across the 3 of their papers we have counts for
3 papers
Using schematic models to understand the microscopic basis for inverted solubility in D-crystallin
Irem Altan, Jennifer McManus, Patrick Charbonneau
Inverted solubility--a crystal melting upon cooling--is observed in a handful of proteins, such as carbomonoxy hemoglobin and D-crystallin. In human D-crystallin, the phenome…
Temperature-dependent non-covalent protein-protein interactions explain normal and inverted solubility in a mutant of human gamma D-crystallin
Amir R. Khan, Susan James, Michelle K. Quinn +3
Protein crystal production is a major bottleneck for the structural characterisation of proteins. To advance beyond large-scale screening, rational strategies for protein crystalli…
The Physics of Protein Self-Assembly
Jennifer J. McManus, Patrick Charbonneau, Emanuela Zaccarelli +1
Understanding protein self-assembly is important for many biological and industrial processes. Proteins can self-assemble into crystals, filaments, gels, and other amorphous aggreg…