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Development of pediatric myeloid leukemia may be related to the repeatedbone-remodeling during bone-growth
Jicun Wang-Michelitsch, Thomas M Michelitsch
Acute myeloid leukemia (AML) and chronic myeloid leukemia (CML) are two major formsof leukemia developed from myeloid cells (MCs). To understand why AML and CML occurin children, w…
Pediatric lymphoma may develop by "one-step" cell transformation of a lymphoid cell
Jicun Wang-Michelitsch, Thomas M Michelitsch
Lymphomas are a large group of neoplasms developed from lymphoid cells (LCs) in lymph nodes (LNs) or lymphoid tissues (LTs). Some forms of lymphomas, including Burkitt lymphoma (BL…
Acute lymphoblastic leukemia may develop as a result of rapid transformation of a lymphoblast triggered by repeated bone-remodeling during bone-growth
Jicun Wang-Michelitsch, Thomas M Michelitsch
Acute lymphoblastic leukemia (ALL) and chronic lymphocytic leukemia (CLL) are two major forms of leukemia that arise from lymphoid cells (LCs). ALL occurs mostly in children and CL…
Three pathways of cell transformation of lymphoid cell: a slow, a rapid, and an accelerated
Jicun Wang-Michelitsch, Thomas M Michelitsch
Lymphoid leukemia (LL) and lymphoma are neoplasms developed from lymphoid cells (LCs). To understand why different forms of LL/lymphoma occur at different ages, we analyzed the eff…
Three potential sources of cell injuries of lymphoid cells associated with developments of lymphoid leukemia and lymphoma
Jicun Wang-Michelitsch, Thomas M Michelitsch
Lymphoid leukemia (LL) and lymphoma are blood cancers developed from lymphoid cells (LCs). To understand the cause and the mechanism of cell transformation of a LC, we studied the…