550 citations · 755 across the 7 of their papers we have counts for
3 papers · 1 filter
Dynamic anticipation by Cdk2/Cyclin A-bound p27 mediates signal integration in cell cycle regulation
Maksym Tsytlonok, Hugo Sanabria, Yuefeng Wang +12
p27 (p27) is an intrinsically disordered protein (IDP) that folds upon binding to cyclin-dependent kinase (Cdk)cyclin complexes (e.g., Cdk2cyclin A), inhibiting thei…
Resolving dynamics and function of transient states in single enzyme molecules
Hugo Sanabria, Dmitro Rodnin, Katherina Hemmen +9
We used a hybrid fluorescence spectroscopic toolkit to monitor T4 Lysozyme (T4L) in action. By unraveling the kinetic and dynamic interplay of the conformational states, we sought…
Revisiting viscosity from the macroscopic to nanoscale regimes
George Hamilton, Zachary Disharoon, Hugo Sanabria
The response of a fluid to deformation by shear stress is known as shear viscosity. This concept arises from a macroscopic view and was first introduced by Sir Isaac Newton. Noneth…