93 citations · 95 across the 2 of their papers we have counts for
4 papers
Automated and optimally FRET-assisted structural modeling
Mykola Dimura, Thomas O. Peulen, Hugo Sanabria +4
FRET experiments can yield state-specific structural information on complex dynamic biomolecular assemblies. However, FRET experiments need to be combined with computer simulations…
Dynamic anticipation by Cdk2/Cyclin A-bound p27 mediates signal integration in cell cycle regulation
Maksym Tsytlonok, Hugo Sanabria, Yuefeng Wang +12
p27 (p27) is an intrinsically disordered protein (IDP) that folds upon binding to cyclin-dependent kinase (Cdk)cyclin complexes (e.g., Cdk2cyclin A), inhibiting thei…
Resolving dynamics and function of transient states in single enzyme molecules
Hugo Sanabria, Dmitro Rodnin, Katherina Hemmen +9
We used a hybrid fluorescence spectroscopic toolkit to monitor T4 Lysozyme (T4L) in action. By unraveling the kinetic and dynamic interplay of the conformational states, we sought…
Revisiting viscosity from the macroscopic to nanoscale regimes
George Hamilton, Zachary Disharoon, Hugo Sanabria
The response of a fluid to deformation by shear stress is known as shear viscosity. This concept arises from a macroscopic view and was first introduced by Sir Isaac Newton. Noneth…