5 papers
Enzyme regulation and mutation in a model serial dilution ecosystem
Amir Erez, Jaime G. Lopez, Yigal Meir +1
Microbial communities are ubiquitous in nature and come in a multitude of forms, ranging from communities dominated by a handful of species to communities containing a wide variety…
Multicellular sensing at a feedback-induced critical point
Michael Vennettilli, Amir Erez, Andrew Mugler
Feedback in sensory biochemical networks can give rise to bifurcations in cells' behavioral response. These bifurcations share many properties with thermodynamic critical points. E…
Cell-to-cell information at a feedback-induced bifurcation point
Amir Erez, Tommy A. Byrd, Michael Vennettilli +1
A ubiquitous way that cells share information is by exchanging molecules. Yet, the fundamental ways that this information exchange is influenced by intracellular dynamics remain un…
Biochemical feedback and its application to immune cells II: dynamics and critical slowing down
Tommy A. Byrd, Amir Erez, Robert M. Vogel +4
Near a bifurcation point, the response time of a system is expected to diverge due to the phenomenon of critical slowing down. We investigate critical slowing down in well-mixed st…
Nutrient levels and trade-offs control diversity in a serial dilution ecosystem
Amir Erez, Jaime G. Lopez, Benjamin Weiner +2
Microbial communities feature an immense diversity of species and this diversity is linked with outcomes ranging from ecosystem stability to medical prognoses. Yet the mechanisms u…