4 citations · 4 across the 2 of their papers we have counts for
5 papers
Maturation of siRNA by strand separation: Steered Molecular dynamics study
Rakesh K Mishra, Sanchita Mukherjee, Dhananjay Bhattacharyya
RNA interference, particularly siRNA induced gene silencing is becoming an important avenue of modern therapeutics. The siRNA is delivered to the cells as short double helical RNA…
Rupture of DNA Aptamer: new insights from simulations
Rakesh Kumar Mishra, Shesh Nath, Sanjay Kumar
Base-pockets (non-complementary base-pairs) in a double-stranded DNA play a crucial role in biological processes. Because of thermal fluctuations, it can lower the stability of DNA…
Statistical Mechanics of DNA Rupture: Theory and Simulations
S. Nath, T. Modi, R. K. Mishra +3
We study the effects of the shear force on the rupture mechanism on a double stranded DNA. Motivated by recent experiments, we perform the atomistic simulations with explicit solve…
Scaling of hysteresis loop of interacting polymers under a periodic force
Rakesh Kumar Mishra, Garima Mishra, Debaprasad Giri +1
Using Langevin Dynamics simulations, we study a simple model of interacting-polymer under a periodic force. The force-extension curve strongly depends on the magnitude of the ampli…
Effect of shear force on the separation of double stranded DNA
Rakesh Kumar Mishra, Garima Mishra, M. S. Li +1
Using the Langevin Dynamics simulation, we have studied the effects of the shear force on the rupture of short double stranded DNA at different temperatures. We show that the ruptu…