51 citations · 211 across the 9 of their papers we have counts for
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q-bio.BM2018
Combinatorial Control through Allostery
Vahe Galstyan, Luke Funk, Tal Einav +1
Many instances of cellular signaling and transcriptional regulation involve switch-like molecular responses to the presence or absence of input ligands. To understand how these res…
q-bio.BM2018★ 40 cited
Harnessing Avidity: Quantifying Entropic and Energetic Effects of Linker Length and Rigidity Required for Multivalent Binding of Antibodies to HIV-1 Spikes
Tal Einav, Shahrzad Yazdi, Aaron Coey +2
Due to the low density of envelope (Env) spikes on the surface of HIV-1, neutralizing IgG antibodies rarely bind bivalently using both antigen-binding arms (Fabs) to crosslink betw…
q-bio.BM2017★ 17 cited
Analysis of Inducer and Operator Binding for Cyclic-AMP Receptor Protein Mutants
Tal Einav, Julia Duque, Rob Phillips
Allosteric transcription factors undergo binding events both at their inducer binding sites as well as at distinct DNA binding domains, and it is often difficult to disentangle the…