101 citations · 474 across the 28 of their papers we have counts for
5 papers · 1 filter
Non-equilibrium phase transitions in hybrid Voronoi models of cell colonies
Mattia Miotto, Giancarlo Ruocco, Matteo Paoluzzi
Eukaryotic cells are characterized by a stiff nucleus whose effect in modeling the collective behavior of cell aggregates is usually underestimated. However, increasing experimenta…
Robust assessment of asymmetric division in colon cancer cells
Domenico Caudo, Chiara Giannattasio, Simone Scalise +6
Asymmetric partition of fate determinants during cell division is a hallmark of cell differentiation. Recent work suggested that such a mechanism is hijacked by cancer cells to inc…
Probing leukemia cells behavior under starvation
Simone Scalise, Giorgio Gosti, Giancarlo Ruocco +2
The ability of a cancer cell population to achieve heterogeneity in their phenotype distributions offers advantages in tumor invasiveness and drug resistance. Studying the mechanis…
Compact assessment of molecular surface complementarities enhances neural network-aided prediction of key binding residues
Greta Grassmann, Lorenzo Di Rienzo, Giancarlo Ruocco +2
Predicting interactions between biomolecules, such as protein-protein complexes, remains a challenging problem. Despite the many advancements done so far, the performances of docki…
Zepyros: A webserver to evaluate the shape complementarity of protein-protein interfaces
Mattia Miotto, Lorenzo Di Rienzo, Leonardo Bo' +2
Shape complementarity of molecular surfaces at the interfaces is a well-known characteristic of protein-protein binding regions, and it is critical in influencing the stability of…