261 citations · 747 across the 6 of their papers we have counts for
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q-bio.GN2018★ 261 cited
OLGA: fast computation of generation probabilities of B- and T-cell receptor amino acid sequences and motifs
Zachary Sethna, Yuval Elhanati, Curtis G. Callan +2
Motivation: High-throughput sequencing of large immune repertoires has enabled the development of methods to predict the probability of generation by V(D)J recombination of T- and…
q-bio.GN2018★ 145 cited
Predicting the spectrum of TCR repertoire sharing with a data-driven model of recombination
Yuval Elhanati, Zachary Sethna, Curtis G. Callan +2
Despite the extreme diversity of T cell repertoires, many identical T-cell receptor (TCR) sequences are found in a large number of individual mice and humans. These widely-shared s…