3 papers
physics.chem-ph2019
Transition path dynamics of a nanoparticle in a bistable optical trap
Niels Zijlstra, Daniel Nettels, Rohit Satija +2
Many processes in chemistry, physics, and biology involve rare events in which the system escapes from a metastable state by surmounting an activation barrier. Examples range from…
physics.bio-ph2019
Depletion interactions modulate coupled folding and binding in crowded environments
Franziska Zosel, Andrea Soranno, Daniel Nettels +1
Intrinsically disordered proteins (IDPs) abound in cellular regulation. Their interactions are often transitory and highly sensitive to salt concentration and posttranslational mod…
q-bio.BM2019
Efficient conversion of chemical energy into mechanical work by Hsp70 chaperones
Salvatore Assenza, Alberto S. Sassi, Ruth Kellner +3
Hsp70 molecular chaperones are abundant ATP-dependent nanomachines that actively reshape non-native, misfolded proteins and assist a wide variety of essential cellular processes. H…