55 citations · 57 across the 5 of their papers we have counts for
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cond-mat.soft2021
A mathematical model for phenotypic heterogeneity in breast cancer with implications for therapeutic strategies
Xin Li, D. Thirumalai
Inevitably, almost all cancer patients develop resistance to targeted therapy. Intratumor heterogeneity (ITH) is a major cause of drug resistance. Mathematical models that explain…
cond-mat.soft2020
Cooperation among tumor cell subpopulations leads to intratumor heterogeneity
Xin Li, D. Thirumalai
Heterogeneity is a hallmark of all cancers. Tumor heterogeneity is found at different levels -- interpatient, intrapatient, and intratumor heterogeneity. All of them pose challenge…
cond-mat.soft2019★ 1 cited
Dual Role of Cell-Cell Adhesion In Tumor Suppression and Proliferation Due to Collective Mechanosensing
Abdul Malmi-Kakkada, Xin Li, Sumit Sinha +1
It is known that mechanical interactions couple a cell to its neighbors, enabling a feedback loop to regulate tissue growth. However, the interplay between cell-cell adhesion stren…