40 citations · 88 across the 9 of their papers we have counts for
9 papers
Anisotropic swelling due to hydration constrains anisotropic elasticity in biomaterial fibers
Xander A. Gouws, Ana Mastnak, Laurent Kreplak +1
Naturally occurring protein fibers often undergo anisotropic swelling when hydrated. Within a tendon, a hydrated collagen fibril's radius expands by 40% but its length only increas…
Torsion and Bistability of Double-Twist Elastomers
Matthew P. Leighton, Laurent Kreplak, Andrew D. Rutenberg
We investigate the elastic properties of anisotropic elastomers with a double-twist director field, which is a model for collagen fibrils or blue phases. We observe a significant P…
Chiral phase-coexistence in compressed double-twist elastomers
Matthew P. Leighton, Laurent Kreplak, Andrew D. Rutenberg
We adapt the theory of anisotropic rubber elasticity to model cross-linked double-twist liquid crystal cylinders such as exhibited in biological systems. In mechanical extension we…
D-band strain underestimates fibril strain for twisted collagen fibrils at low strains
Matthew P. Leighton, Andrew D. Rutenberg, Laurent Kreplak
Collagen fibrils are the main structural component of load-bearing tissues such as tendons, ligaments, skin, the cornea of the eye, and the heart. The D-band of collagen fibrils is…
Non-equilibrium Growth and Twist of Cross-Linked Collagen Fibrils
Matthew P. Leighton, Laurent Kreplak, Andrew D. Rutenberg
The lysyl oxidase (LOX) enzyme that catalyses cross-link formation during the assembly of collagen fibrils in vivo is too large to diffuse within assembled fibrils, and so is incom…
Phase-field collagen fibrils: Coupling chirality and density modulations
Samuel Cameron, Laurent Kreplak, Andrew D. Rutenberg
To describe the interaction between longitudinal density modulations along collagen fibrils (the D-band) with the radial twist-field of molecular orientation (double-twist), we cou…
Polymorphism of stable collagen fibrils
Samuel Cameron, Laurent Kreplak, Andrew D. Rutenberg
Collagen fibrils are versatile self-assembled structures that provide mechanical integrity within mammalian tissues. The radius of collagen fibrils vary widely depending on experim…
Uniform spatial distribution of collagen fibril radii within tendon implies local activation of pC-collagen at individual fibrils
Andrew D Rutenberg, Aidan I Brown, Laurent Kreplak
Collagen fibril cross-sectional radii show no systematic variation between the interior and the periphery of fibril bundles, indicating an effectively constant rate of collagen inc…
An equilibrium double-twist model for the radial structure of collagen fibrils
Aidan I Brown, Laurent Kreplak, Andrew D Rutenberg
Mammalian tissues contain networks and ordered arrays of collagen fibrils originating from the periodic self-assembly of helical 300 nm long tropocollagen complexes. The fibril rad…