79 citations · 174 across the 15 of their papers we have counts for
4 papers · 1 filter
The Site Frequency Spectrum in an Exponentially Growing Population with Selection
Armaan Ahmed, Jasmine Foo, Einar Gunnarsson +1
We consider a supercritical two-type continuous-time linear birth-death process with mutation and selection, in which wild-type individuals give rise to mutant offspring with a lar…
Spread of premalignant mutant clones and cancer initiation in multilayered tissue
Jasmine Foo, Einar Bjarki Gunnarsson, Kevin Leder +1
Over 80% of human cancers originate from the epithelium, which covers the outer and inner surfaces of organs and blood vessels. In stratified epithelium, the bottom layers are occu…
Mutation timing in a spatial model of evolution
Jasmine Foo, Kevin Leder, Jason Schweinsberg
Motivated by models of cancer formation in which cells need to acquire mutations to become cancerous, we consider a spatial population model in which the population is represen…
Dynamics of cancer recurrence
Jasmine Foo, Kevin Leder
Mutation-induced drug resistance in cancer often causes the failure of therapies and cancer recurrence, despite an initial tumor reduction. The timing of such cancer recurrence is…