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20152023
most citedNegative membrane capacitance of outer hair cells: electromechanical coupling near resonance

26 citations · 57 across the 9 of their papers we have counts for

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physics.bio-ph2023

Membrane Thickness Sensitivity of Avian Prestin: Implications

Kuni H Iwasa

Avian prestin is sensitive to membrane thickness as much as mammalian prestin, which undergoes conformational transitions in membrane area and thereby drives length changes of the…

physics.bio-ph2021★ 2 cited

Of Mice and Chickens: Revisiting the RC Time Constant Problem

Kuni H. Iwasa

Avian hair cells depend on electrical resonance for frequency selectivity. The upper bound of the frequency range is limited by the RC time constant of hair cells because the sharp…

physics.bio-ph2020★ 1 cited

Not so presto? Outcomes of sluggish prestin in outer hair cells

Kuni H. Iwasa

Prestin (SLC26A5), a protein essential for the sensitivity of the mammalian ear, was so named from \emph{presto}. The assumption was that this membrane protein supports fast moveme…

physics.bio-ph2020

Frequency dependence of prestin: Intrinsic transition rates and viscoelastic relaxation

Kuni H Iwasa

Outer hair cells in the inner ear is important for the sensitivity, frequency selectivity, and dynamic range of the mammalian ear. Such a physiological role of outer hair cells is…

physics.bio-ph2018★ 6 cited

Kinetic Membrane Model of Outer Hair Cells I: Motile Elements with Two Conformational States

Kuni H. Iwasa

The effectiveness of outer hair cells (OHCs) in amplifying the motion of the organ of Corti, and thereby contributing to the sensitivity of mammalian hearing, depends on the mechan…

physics.bio-ph2018

The outer hair cell of the organ of Corti possesses a voltage-dependent motile frequency response: evidence for the frequency-dependent compliance of prestin

Joseph Santos-Sacchi, Kuni Iwasa, Winston Tan

The outer hair cell (OHC) of the organ of Corti underlies a mechanically based process that enhances hearing, termed cochlear amplification. The cell possesses a unique motor prote…

physics.bio-ph2017★ 26 cited

Negative membrane capacitance of outer hair cells: electromechanical coupling near resonance

Kuni H Iwasa

The ability of the mammalian ear in processing high frequency sounds, up to 100 kHz, is based on the capability of outer hair cells (OHCs) responding to stimulation at high f…

physics.bio-ph2016★ 18 cited

Energy output from a single outer hair cell

Kuni H Iwasa

Electromotility of outer hair cells (OHCs) has been extensively studied with in vitro experiments because of its physiological significance in the cochlear amplifier, which provide…

physics.bio-ph2015★ 3 cited

A molecule that detects the length of DNA by using chain fluctuations

Kuni H. Iwasa, Ana Maria Florescu

A class of nucleosome remodeling motors translocate nucleosomes, to which they are attached, toward the middle of DNA chain in the presence of ATP during in vitro experiments. Such…

physics.bio-ph2015★ 1 cited

The avian tectorial membrane: Why is it tapered?

Kuni H. Iwasa, Anthony J. Ricci

While the mammalian- and the avian inner ears have well defined tonotopic organizations as well as hair cells specialized for motile and sensing roles, the structural organization…