activity
20152023
most citedNegative membrane capacitance of outer hair cells: electromechanical coupling near resonance

26 citations · 57 across the 9 of their papers we have counts for

collaborators

10 papers

physics.bio-ph2023

Membrane Thickness Sensitivity of Avian Prestin: Implications

Kuni H Iwasa

Avian prestin is sensitive to membrane thickness as much as mammalian prestin, which undergoes conformational transitions in membrane area and thereby drives length changes of the…

physics.bio-ph2021★ 2 cited

Of Mice and Chickens: Revisiting the RC Time Constant Problem

Kuni H. Iwasa

Avian hair cells depend on electrical resonance for frequency selectivity. The upper bound of the frequency range is limited by the RC time constant of hair cells because the sharp…

physics.bio-ph2020★ 1 cited

Not so presto? Outcomes of sluggish prestin in outer hair cells

Kuni H. Iwasa

Prestin (SLC26A5), a protein essential for the sensitivity of the mammalian ear, was so named from \emph{presto}. The assumption was that this membrane protein supports fast moveme…

physics.bio-ph2020

Frequency dependence of prestin: Intrinsic transition rates and viscoelastic relaxation

Kuni H Iwasa

Outer hair cells in the inner ear is important for the sensitivity, frequency selectivity, and dynamic range of the mammalian ear. Such a physiological role of outer hair cells is…

physics.bio-ph2018★ 6 cited

Kinetic Membrane Model of Outer Hair Cells I: Motile Elements with Two Conformational States

Kuni H. Iwasa

The effectiveness of outer hair cells (OHCs) in amplifying the motion of the organ of Corti, and thereby contributing to the sensitivity of mammalian hearing, depends on the mechan…

physics.bio-ph2018

The outer hair cell of the organ of Corti possesses a voltage-dependent motile frequency response: evidence for the frequency-dependent compliance of prestin

Joseph Santos-Sacchi, Kuni Iwasa, Winston Tan

The outer hair cell (OHC) of the organ of Corti underlies a mechanically based process that enhances hearing, termed cochlear amplification. The cell possesses a unique motor prote…