50 citations · 111 across the 5 of their papers we have counts for
5 papers
Exponential volume dependence of entropy-current fluctuations at first-order phase transitions in chemical reaction networks
Basile Nguyen, Udo Seifert
In chemical reaction networks, bistability can only occur far from equilibrium. It is associated with a first-order phase transition where the control parameter is the thermodynami…
Stochastic thermodynamics of chemical reactions coupled to finite reservoirs: A case study for the Brusselator
Jonas H. Fritz, Basile Nguyen, Udo Seifert
Biomolecular processes are typically modeled using chemical reaction networks coupled to infinitely large chemical reservoirs. A difference in chemical potential between these rese…
Interlinked GTPase cascades provide a motif for both robust switches and oscillators
Andreas Ehrmann, Basile Nguyen, Udo Seifert
GTPases regulate a wide range of cellular processes, such as intracellular vesicular transport, signal transduction, and protein translation. These hydrolase enzymes operate as bio…
Phase transition in thermodynamically consistent biochemical oscillators
Basile Nguyen, Udo Seifert, Andre C. Barato
Biochemical oscillations are ubiquitous in living organisms. In an autonomous system, not influenced by an external signal, they can only occur out of equilibrium. We show that the…
Thermodynamic bounds on the ultra- and infra-affinity of Hsp70 for its substrates
Basile Nguyen, David Hartich, Udo Seifert +1
The 70 kDa Heat Shock Proteins Hsp70 have several essential functions in living systems, such as protecting cells against protein aggregation, assisting protein folding, remodeling…