212 citations · 382 across the 10 of their papers we have counts for
3 papers · 1 filter
Irreversibility in Bacterial Regulatory Networks
Yi Zhao, Thomas P. Wytock, Kimberly A. Reynolds +1
Irreversibility, in which a transient perturbation leaves a system in a new state, is an emergent property in systems of interacting entities. This property has well-established im…
Cell reprogramming design by transfer learning of functional transcriptional networks
Thomas P. Wytock, Adilson E. Motter
Recent developments in synthetic biology, next-generation sequencing, and machine learning provide an unprecedented opportunity to rationally design new disease treatments based on…
Experimental evolution of diverse Escherichia coli metabolic mutants identifies genetic loci for convergent adaptation of growth rate
Thomas P. Wytock, Aretha Fiebig, Jonathan W. Willett +4
Cell growth is determined by substrate availability and the cell's metabolic capacity to assimilate substrates into building blocks. Metabolic genes that determine growth rate may…