37 citations · 82 across the 3 of their papers we have counts for
4 papers
Extreme antagonism arising from gene-environment interactions
Thomas P. Wytock, Manjing Zhan, Adrian Jinich +3
Antagonistic interactions in biological systems, which occur when one perturbation blunts the effect of another, are typically interpreted as evidence that the two perturbations im…
Distinguishing Cell Phenotype Using Cell Epigenotype
Thomas P. Wytock, Adilson E. Motter
The relationship between microscopic observations and macroscopic behavior is a fundamental open question in biophysical systems. Here, we develop a unified approach that---in cont…
Predicting Growth Rate from Gene Expression
Thomas P. Wytock, Adilson E. Motter
Growth rate is one of the most important and most complex phenotypic characteristics of unicellular microorganisms, which determines the genetic mutations that dominate at the popu…
Experimental evolution of diverse Escherichia coli metabolic mutants identifies genetic loci for convergent adaptation of growth rate
Thomas P. Wytock, Aretha Fiebig, Jonathan W. Willett +4
Cell growth is determined by substrate availability and the cell's metabolic capacity to assimilate substrates into building blocks. Metabolic genes that determine growth rate may…