4 papers
Optimization of vaccination for COVID-19 in the midst of a pandemic
Qi Luo, Ryan Weightman, Sean T. McQuade +6
During the Covid-19 pandemic a key role is played by vaccination to combat the virus. There are many possible policies for prioritizing vaccines, and different criteria for optimiz…
Integrated Framework of Vehicle Dynamics, Instabilities, Energy Models, and Sparse Flow Smoothing Controllers
Jonathan W. Lee, George Gunter, Rabie Ramadan +25
This work presents an integrated framework of: vehicle dynamics models, with a particular attention to instabilities and traffic waves; vehicle energy models, with particular atten…
Metabolic graphs, LIFE method and the modeling of drug action on Mycobacterium tuberculosis
Sean T. McQuade, Nathaniel J. Merrill, Benedetto Piccoli
This paper serves as a framework for designing advanced models for drug action on metabolism. Drug treatment may affect metabolism by either enhancing or inhibiting metabolic react…
Stability of Metabolic Networks via Linear-In-Flux-Expressions
Nathaniel J. Merrill, Zheming An, Sean T. McQuade +4
The methodology named LIFE (Linear-in-Flux-Expressions) was developed with the purpose of simulating and analyzing large metabolic systems. With LIFE, the number of model parameter…