2 papers
q-bio.SC2020
Steady-state fluctuations of a genetic feedback loop with fluctuating rate parameters using the unified colored noise approximation
James Holehouse, Abhishek Gupta, Ramon Grima
A common model of stochastic auto-regulatory gene expression describes promoter switching via cooperative protein binding, effective protein production in the active state and dilu…
q-bio.SC2019
Stochastic modeling of auto-regulatory genetic feedback loops: a review and comparative study
James Holehouse, Zhixing Cao, Ramon Grima
Auto-regulatory feedback loops are one of the most common network motifs. A wide variety of stochastic models have been constructed to understand how the fluctuations in protein nu…