1 citations · 1 across the 4 of their papers we have counts for
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stat.ME2020
What Were They Thinking? Pharmacologic priors implicit in a choice of 3+3 dose-escalation design
David C. Norris
If explicit, formal consideration of clinical pharmacology at all informs the design and conduct of modern oncology dose-finding trials, the designs themselves hardly attest to thi…
stat.ME2020★ 1 cited
Retrospective analysis of a fatal dose-finding trial
David C. Norris
The commonplace description of phase 1 clinical trials in oncology as "primarily concerned with safety" is belied by their near universal adoption of dose-escalation practices whic…