activity
20202023
most citedAn Integrated Biological Optimization framework for proton SBRT FLASH treatment planning allows dose, dose rate, and LET optimization using patient-specific ridge filters

54 citations · 139 across the 12 of their papers we have counts for

collaborators

13 papers

physics.med-ph2023

Streamlined Pin-Ridge-Filter Design for Single-energy Proton FLASH Planning

Chaoqiong Ma, Jun Zhou, Chih-Wei Chang +5

Purpose: This study explored the feasibility of a streamlined pin-shaped ridge filter (pin-RF) design for single-energy proton FLASH planning. Methods: An inverse planning framewor…

physics.med-ph2022★ 4 cited

A Retrospective Study on the Investigation of Potential Clinical Benefits of Online Adaptive Proton Therapy for Head and Neck Cancer

Chih-Wei Chang, Duncan Bohannon, Zhen Tian +6

Online adaptive proton therapy (APT) is an ideal solution theoretically, which however is challenging to proton clinics. Although multiple groups have been endeavoring to develop o…

physics.med-ph2022★ 1 cited

Deep Learning-based Protoacoustic Signal Denoising for Proton Range Verification

Jing Wang, James J. Sohn, Yang Lei +5

Objective: Proton therapy offers an advantageous dose distribution compared to the photon therapy, since it deposits most of the energy at the end of range, namely the Bragg peak (…

physics.med-ph2022★ 6 cited

Early in vivo Radiation Damage Quantification for Pediatric Craniospinal Irradiation Using Longitudinal MRI for Intensity Modulated Proton Therapy

Chih-Wei Chang, Matt Goette, Nadja Kadom +8

Purpose: Proton vertebral body sparing craniospinal irradiation (VBS CSI) treats the thecal sac while avoiding the anterior vertebral bodies in effort to reduce myelosuppression an…

physics.med-ph2022★ 1 cited

Deep learning-based Fast Volumetric Image Generation for Image-guided Proton FLASH Radiotherapy

Chih-Wei Chang, Yang Lei, Tonghe Wang +7

Proton FLASH therapy leverages ultra-high dose-rate radiation to enhance the sparing of organs at risk without compromising tumor control probability. To prepare for the delivery o…

physics.med-ph2022★ 12 cited

MRI-based Material Mass Density and Relative Stopping Power Estimation via Deep Learning for Proton Therapy

Yuan Gao, Chih-Wei Chang, Sagar Mandava +10

Magnetic Resonance Imaging (MRI) is increasingly incorporated into treatment planning, because of its superior soft tissue contrast used for tumor and soft tissue delineation versu…