activity
20202026
most citedAn Integrated Biological Optimization framework for proton SBRT FLASH treatment planning allows dose, dose rate, and LET optimization using patient-specific ridge filters

54 citations · 78 across the 8 of their papers we have counts for

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Showing 2022Show all

4 papers · 1 filter

physics.med-ph2022★ 2 cited

Validation of the Quantum Physics Processes Underlying the Integrated Optimization of Proton FLASH Radiotherapy

Nathan Harrison, Serdar Charyyev, Cristina Oancea +6

FLASH is a new treatment modality that requires optimization of dose, dose rate, and LET. Here we validate these three quantities under FLASH conditions, which includes the quantum…

physics.med-ph2022★ 17 cited

Measurement of the time structure of FLASH beams using prompt gamma rays and secondary neutrons as surrogates

Serdar Charyyev, Ruirui Liu, Xiaofeng Yang +5

We aim to investigate the feasibility of online monitoring of irradiation time (IRT) and scan time for FLASH radiotherapy using a pixelated semiconductor detector. Measurements of…

physics.med-ph2022★ 1 cited

Characterization of 250 MeV protons from Varian ProBeam pencil beam scanning system for FLASH radiation therapy

Serdar Charyyev, Chih-Wei Chang, Mingyao Zhu +3

Recently, shoot-through proton FLASH has been proposed where the highest energy is extracted from the cyclotron to maximize the dose rate (DR). Even though our proton pencil beam s…

physics.med-ph2022★ 54 cited

An Integrated Biological Optimization framework for proton SBRT FLASH treatment planning allows dose, dose rate, and LET optimization using patient-specific ridge filters

Ruirui Liu, Serdar Charyyev, Niklas Wahl +10

Purpose: Patient-specific ridge filters can modulate proton energy to obtain a conformal dose. We describe a new framework for optimization of filter design and spot maps to meet t…