54 citations · 78 across the 8 of their papers we have counts for
8 papers
Clinical Commissioning of the First Ultra-Compact Gantry-less Upright Proton Therapy System
Serdar Charyyev, Adam Johansson, Zhuoran Jiang +17
This study reports the comprehensive clinical commissioning and benchmarking of a novel ultra-compact, gantry-free, upright PT system.
High-speed proton therapy within a short breath-hold
Vivek Maradia, Nick Yue, Adam Molzahn +4
Proton therapy provides superior dose conformity compared with photon radiotherapy, concentrating radiation within the tumor while sparing adjacent healthy tissue. This advantage h…
A novel inverse algorithm to solve IPO-IMPT of proton FLASH therapy with sparse filters
Nathan Harrison, Minglei Kang, Ruirui Liu +9
Purpose:The recently proposed IPO-IMPT framework allows simultaneous optimization of dose, dose rate, and LET for FLASH treatment planning. Finding solutions to IPO-IMPT is difficu…
Validation of the Quantum Physics Processes Underlying the Integrated Optimization of Proton FLASH Radiotherapy
Nathan Harrison, Serdar Charyyev, Cristina Oancea +6
FLASH is a new treatment modality that requires optimization of dose, dose rate, and LET. Here we validate these three quantities under FLASH conditions, which includes the quantum…
Measurement of the time structure of FLASH beams using prompt gamma rays and secondary neutrons as surrogates
Serdar Charyyev, Ruirui Liu, Xiaofeng Yang +5
We aim to investigate the feasibility of online monitoring of irradiation time (IRT) and scan time for FLASH radiotherapy using a pixelated semiconductor detector. Measurements of…
Characterization of 250 MeV protons from Varian ProBeam pencil beam scanning system for FLASH radiation therapy
Serdar Charyyev, Chih-Wei Chang, Mingyao Zhu +3
Recently, shoot-through proton FLASH has been proposed where the highest energy is extracted from the cyclotron to maximize the dose rate (DR). Even though our proton pencil beam s…
An Integrated Biological Optimization framework for proton SBRT FLASH treatment planning allows dose, dose rate, and LET optimization using patient-specific ridge filters
Ruirui Liu, Serdar Charyyev, Niklas Wahl +10
Purpose: Patient-specific ridge filters can modulate proton energy to obtain a conformal dose. We describe a new framework for optimization of filter design and spot maps to meet t…
Learning-Based Synthetic Dual Energy CT Imaging from Single Energy CT for Stopping Power Ratio Calculation in Proton Radiation Therapy
Serdar Charyyev, Tonghe Wang, Yang Lei +7
Purpose: Dual-energy CT (DECT) has been shown to derive stopping power ratio (SPR) map with higher accuracy than conventional single energy CT (SECT) by obtaining the energy depend…