112 citations · 158 across the 12 of their papers we have counts for
3 papers · 1 filter
Parameter estimation in ODEs: assessing the potential of local and global solvers
M. Fernández de Dios, Ángel M. González-Rueda, Julio R. Banga +2
We consider the problem of parameter estimation in dynamic systems described by ordinary differential equations. A review of the existing literature emphasizes the need for determi…
Multicriteria global optimization for biocircuit design
Irene Otero-Muras, Julio R. Banga
One of the challenges in Synthetic Biology is to design circuits with increasing levels of complexity. While circuits in Biology are complex and subject to natural tradeoffs, most…
MEIGO: an open-source software suite based on metaheuristics for global optimization in systems biology and bioinformatics
Jose A Egea, David Henriques, Thomas Cokelaer +3
Optimization is key to solve many problems in computational biology. Global optimization methods provide a robust methodology, and metaheuristics in particular have proven to be th…