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stat.ME2025
Leveraging External Data for Testing Experimental Therapies with Biomarker Interactions in Randomized Clinical Trials
Boyu Ren, Federico Ferrari, Sandra Fortini +2
In oncology the efficacy of novel therapeutics often differs across patient subgroups, and these variations are difficult to predict during the initial phases of the drug developme…
stat.AP2025
A cautious use of auxiliary outcomes for decision-making in randomized clinical trials
Massimiliano Russo, Steffen Ventz, Lorenzo Trippa
Clinical trials often collect data on multiple outcomes, such as overall survival (OS), progression-free survival (PFS), and response to treatment (RT). In most cases, however, stu…