activity
20172023
most citedMetabolite mediated modeling of microbial community dynamics captures emergent behavior more effectively than species-species modeling

27 citations · 76 across the 9 of their papers we have counts for

collaborators

9 papers

q-bio.QM2023

Combining Compositional Data Sets Introduces Error in Covariance Network Reconstruction

James D. Brunner, Aaron J. Robinson, Patrick S. G. Chain

Microbial communities are diverse biological systems that include taxa from across multiple kingdoms of life. Notably, interactions between bacteria and fungi play a significant ro…

q-bio.QM2023

Inferring microbial interactions with their environment from genomic and metagenomic data

James D. Brunner, Laverne A. Gallegos-Graves, Marie E. Kroeger

Microbial communities assemble through a complex set of interactions between microbes and their environment, and the resulting metabolic impact on the host ecosystem can be profoun…

q-bio.QM2022

Metabolic Model-based Ecological Modeling for Probiotic Design

James D. Brunner, Nicholas Chia

The microbial community composition in the human gut has a profound effect on human health. This observation has lead to extensive use of microbiome therapies, including over-the-c…

q-bio.MN2020

A dynamical system model for predicting gene expression from the epigenome

James Brunner, Jacob Kim, Timothy Downing +2

Gene regulation is an important fundamental biological process. The regulation of gene expression is managed through a variety of methods including epigenetic processes (e.g., DNA…

q-bio.PE2020

Confidence in the dynamic spread of epidemics under biased sampling conditions

James D. Brunner, Nicholas Chia

The interpretation of sampling data plays a crucial role in policy response to the spread of a disease during an epidemic, such as the COVID-19 epidemic of 2020. However, this is a…

math.DS2020★ 12 cited

On classes of reaction networks and their associated polynomial dynamical systems

David F. Anderson, James D. Brunner, Gheorghe Craciun +1

In the study of reaction networks and the polynomial dynamical systems that they generate, special classes of networks with important properties have been identified. These include…