3 papers
q-bio.QM2020
Network reinforcement driven drug repurposing for COVID-19 by exploiting disease-gene-drug associations
Yonghyun Nam, Jae-Seung Yun, Seung Mi Lee +7
Currently, the number of patients with COVID-19 has significantly increased. Thus, there is an urgent need for developing treatments for COVID-19. Drug repurposing, which is the pr…
cs.LG2019
Drug-drug interaction prediction based on co-medication patterns and graph matching
Wen-Hao Chiang, Li Shen, Lang Li +1
Background: The problem of predicting whether a drug combination of arbitrary orders is likely to induce adverse drug reactions is considered in this manuscript. Methods: Novel ker…
cs.IR2018
Drug Recommendation toward Safe Polypharmacy
Wen-Hao Chiang, Li Shen, Lang Li +1
Adverse drug reactions (ADRs) induced from high-order drug-drug interactions (DDIs) due to polypharmacy represent a significant public health problem. In this paper, we formally fo…