activity
20222026
most citedEvolutionary Khovanov homology

9 citations · 17 across the 12 of their papers we have counts for

collaborators

12 papers

math.GT2026

Khovanov homology: pro-tangles, derived colimits and spectral sequences

Jian Liu, Kefeng Liu, Li Shen

This paper introduces \emph{pro-tangles}, a natural generalization of classical tangles, which are functors from the Boolean cube to Bar-Natan's cobordism category. By employing th…

math.GT2025

Khovanov homology of tangles: algorithm and computation

Li Shen, Jian Liu, Guo-Wei Wei

Knot, link, and tangle theory is crucial in both mathematical theory and practical application, including quantum physics, molecular biology, and structural chemistry. Unlike knots…

math.GT2025

Computing Khovanov homology of tangles

Li Shen, Jian Liu, Guo-Wei Wei

The computation of Khovanov homology for tangles has significant potential applications, yet explicit computational studies remain limited. In this work, we present a method for co…

math.AT2025

Topological Sequence Analysis of Genomes: Delta Complex approaches

Jian Liu, Li Shen, Dong Chen +1

Algebraic topology has been widely applied to point cloud data to capture geometric shapes and topological structures. However, its application to genome sequence analysis remains…

q-bio.GN2025

Topological Sequence Analysis of Genomes: Category theory Approaches

Jian Liu, Li Shen, Mushal Zia +1

Sequence data, such as DNA, RNA, and protein sequences, exhibit intricate, multi-scale structures that pose significant challenges for conventional analysis methods, particularly t…

math.GT2024

Persistent Khovanov homology of tangles

Jian Liu, Li Shen, Guo-Wei Wei

Knot data analysis (KDA), which studies data with curve-type structures such as knots, links, and tangles, has emerging as a promising geometric topology approach in data science.…

q-bio.BM2024

Mayer-homology learning prediction of protein-ligand binding affinities

Hongsong Feng, Li Shen, Jian Liu +1

Artificial intelligence-assisted drug design is revolutionizing the pharmaceutical industry. Effective molecular features are crucial for accurate machine learning predictions, and…

math.GT2024★ 9 cited

Evolutionary Khovanov homology

Li Shen, Jian Liu, Guo-Wei Wei

Knot theory is a study of the embedding of closed circles into three-dimensional Euclidean space, motivated the ubiquity of knots in daily life and human civilization. However, the…

math.AT2023

Persistent Mayer homology and persistent Mayer Laplacian

Li Shen, Jian Liu, Guo-Wei Wei

In algebraic topology, the differential (i.e., boundary operator) typically satisfies . However, the generalized differential for an integer has been s…

math.AT2023★ 8 cited

ChatGPT for Computational Topology

Jian Liu, Li Shen, Guo-Wei Wei

ChatGPT represents a significant milestone in the field of artificial intelligence (AI), finding widespread applications across diverse domains. However, its effectiveness in mathe…

math.GT2023

Knot data analysis using multiscale Gauss link integral

Li Shen, Hongsong Feng, Fengling Li +3

In the past decade, topological data analysis (TDA) has emerged as a powerful approach in data science. The main technique in TDA is persistent homology, which tracks topological i…

q-bio.MN2022

Machine learning analysis of cocaine addiction informed by DAT, SERT, and NET-based interactome networks

Hongsong Feng, Kaifu Gao, Dong Chen +3

Cocaine addiction is a psychosocial disorder induced by the chronic use of cocaine and causes a large of number deaths around the world. Despite many decades' effort, no drugs have…