A general reaction network unifies the aggregation behaviour of the A$\beta$42 peptide and its variants

Georg Meisl, Xiaoting Yang, Christopher M. Dobson +2

The amyloid $\beta$ peptide (A$\beta$42), whose aggregation is associated with Alzheimer's disease, is an amphiphatic peptide with a high propensity to self-assemble. A$\beta$42 has a net nega…