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q-bio.PE2020
About the Protein Space Vastness
Jorge A. Vila
An accurate estimation of the Protein Space size, in light of the factors that govern it, is a long-standing problem and of paramount importance in evolutionary biology, since it d…
q-bio.BM2020
Metamorphic Proteins in light of the Anfinsen Dogma
Jorge A. Vila
It is a common belief that metamorphic proteins challenge the Anfinsen thermodynamic hypothesis (or dogma). Here we argue against this view aims to show that metamorphic proteins n…