287 citations · 3.4k across the 49 of their papers we have counts for
53 papers
Information content and optimization of self-organized developmental systems
David B. Brückner, Gašper Tkačik
A key feature of many developmental systems is their ability to self-organize spatial patterns of functionally distinct cell fates. To ensure proper biological function, such patte…
Path Weight Sampling: Exact Monte Carlo Computation of the Mutual Information between Stochastic Trajectories
Manuel Reinhardt, Gašper Tkačik, Pieter Rein ten Wolde
Most natural and engineered information-processing systems transmit information via signals that vary in time. Computing the information transmission rate or the information encode…
Token-driven totally asymmetric simple exclusion process
Bor Kavčič, Gašper Tkačik
We consider a family of totally asymmetric simple exclusion processes (TASEPs), consisting of particles on a lattice that require binding by a "token" in various physical configura…
Statistical modeling of adaptive neural networks explains coexistence of avalanches and oscillations in resting human brain
Fabrizio Lombardi, Selver Pepić, Oren Shriki +2
Neurons in the brain are wired into adaptive networks that exhibit a range of collective dynamics. Oscillations, for example, are paradigmatic synchronous patterns of neural activi…
A Tight Upper Bound on Mutual Information
Michal Hledík, Thomas R. Sokolowski, Gašper Tkačik
We derive a tight lower bound on equivocation (conditional entropy), or equivalently a tight upper bound on mutual information between a signal variable and channel outputs. The bo…
Estimating information in time-varying signals
Sarah A Cepeda-Humerez, Jakob Ruess, Gašper Tkačik
Across diverse biological systems -- ranging from neural networks to intracellular signaling and genetic regulatory networks -- the information about changes in the environment is…