14 citations · 15 across the 4 of their papers we have counts for
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stat.ME2020★ 14 cited
A novel estimand to adjust for rescue treatment in clinical trials
Hege Michiels, Cristina Sotto, An Vandebosch +1
The interpretation of randomised clinical trial results is often complicated by intercurrent events. For instance, rescue medication is sometimes given to patients in response to w…
stat.ME2020
Efficient, Doubly Robust Estimation of the Effect of Dose Switching for Switchers in a Randomised Clinical Trial
Kelly Van Lancker, An Vandebosch, Stijn Vansteelandt
Motivated by a clinical trial conducted by Janssen Pharmaceuticals in which a flexible dosing regimen is compared to placebo, we evaluate how switchers in the treatment arm (i.e.,…