60 citations · 232 across the 11 of their papers we have counts for
11 papers
Temporal signals drive the emergence of multicellular information networks
Guanyu Li, Ryan LeFebre, Alia Starman +3
Coordinated responses to environmental stimuli are critical for multicellular organisms. To overcome the obstacles of cell-to-cell heterogeneity and noisy signaling dynamics within…
Extracellular Matrix regulates the morphodynamics of 3D migrating cancer cells
Christopher Z. Eddy, Helena Raposo, Ryan Wong +1
Cell shape is linked to cell function. The significance of cell morphodynamics, namely the temporal fluctuation of cell shape, is much less understood. Here we study the morphodyna…
Modeling Multi-Cellular Dynamics Regulated by ECM-Mediated Mechanical Communication via Active Particles with Polarized Effective Attraction
Yu Zheng, Qihui Fan, Christopher Eddy +4
Collective cell migration is crucial to many physiological and pathological processes. Recent experimental studies have indicated that the active traction forces generated by migra…
Modeling cell migration regulated by cell-ECM micromechanical coupling
Yu Zheng, Hanqing Nan, Qihui Fan +6
Cell migration in fibreous extracellular matrix (ECM) is crucial to many physiological and pathological processes such as tissue regeneration, immune response and cancer progressio…
Collective dynamics and self-organization of active particles on random networks
Hanqing Nan, Yu Zheng, Shaohua Chen +5
Collective cell migration in 3D extracellular matrix (ECM) is crucial to many physiological and pathological processes. Migrating cells can generate active pulling forces via actin…
Collective ECM remodeling organizes 3D collective cancer invasion
Jihan Kim, Yu Zheng, Amani A. Alobaidi +4
Tumor metastasis, traditionally considered as random spreading of individual cancer cells, has been shown to also involve coordinated collective invasion in the tissue space. Here…
The morphodynamics of 3D migrating cancer cells
Christopher Z. Eddy, Xinyao Wang, Fuxin Li +1
Cell shape is an important biomarker that is directly linked to cell function. However, cell morphodynamics, namely the temporal fluctuation of cell shape is much less understood.…
Probing Three-dimensional Collective Cancer Invasion with DIGME
Amani A. Alobaidi, Bo Sun
Multicellular migration and pattern formation play important roles in developmental biology, cancer metastasis and wound healing. To understand the collective cell dynamics in thre…
Dynamic sampling and information encoding in biochemical networks
Garrett D. Potter, Tommy A. Byrd, Andrew Mugler +1
Cells use biochemical networks to translate environmental information into intracellular responses. These responses can be highly dynamic, but how the information is encoded in the…
Heterogeneous Force Chains in Cellularized Biopolymer Network
Long Liang, Christopher Jones, Bo Sun +1
Biopolymer Networks play an important role in coordinating and regulating collective cellular dynamics via a number of signaling pathways. Here, we investigate the mechanical respo…
Communication shapes sensory response in multicellular networks
Garrett D Potter, Tommy A Byrd, Andrew Mugler +1
Collective sensing by interacting cells is observed in a variety of biological systems, and yet a quantitative understanding of how sensory information is collectively encoded is l…