1 citations · 1 across the 4 of their papers we have counts for
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Genome analysis and pleiotropy assessment using causal networks with loss of function mutation and metabolomics
Azam Yazdani, Akram Yazdani, Sarah H. Elsea +4
Background: Many genome-wide association studies have detected genomic regions associated with traits, yet understanding the functional causes of association often remains elusive.…
A Multi-Trait Approach Identified Genetic Variants Including a Rare Mutation in RGS3 with Impact on Abnormalities of Cardiac Structure/Function
Akram Yazdani, Azam Yazdani, Raúl Méndez Giráldez +2
Heart failure is a major cause for premature death. Given heterogeneity of the heart failure syndrome, identifying genetic determinants of cardiac function and structure may provid…
Integrated systems approach identifies pathways from the genome to triglycerides through a metabolomic causal network
Azam Yazdani, Akram Yazdani, Philip L. Lorenzi +1
Introduction: To leverage functionality and clinical relevance into understanding systems biology, one needs to understand the pathway of the genetic effects on risk factors/diseas…