3 citations · 4 across the 6 of their papers we have counts for
5 papers · 1 filter
Transcriptomic Causal Networks identified patterns of differential gene regulation in human brain from Schizophrenia cases versus controls
Akram Yazdani, Raul Mendez-Giraldez, Michael R Kosorok +1
Common and complex traits are the consequence of the interaction and regulation of multiple genes simultaneously, which work in a coordinated way. However, the vast majority of stu…
A Multi-Trait Approach Identified Genetic Variants Including a Rare Mutation in RGS3 with Impact on Abnormalities of Cardiac Structure/Function
Akram Yazdani, Azam Yazdani, Raúl Méndez Giráldez +2
Heart failure is a major cause for premature death. Given heterogeneity of the heart failure syndrome, identifying genetic determinants of cardiac function and structure may provid…
Integrated systems approach identifies pathways from the genome to triglycerides through a metabolomic causal network
Azam Yazdani, Akram Yazdani, Philip L. Lorenzi +1
Introduction: To leverage functionality and clinical relevance into understanding systems biology, one needs to understand the pathway of the genetic effects on risk factors/diseas…
Effect of Blast Exposure on Gene-Gene Interactions
Akram Yazdani
Repeated exposure to low-level blast may initiate a range of adverse health problem such as traumatic brain injury (TBI). Although many studies successfully identified genes associ…
Insights into Complex Brain Functions Related to Schizophrenia Disorder through Causal Network Analysis
Akram Yazdani, Raul Mendez Giraldez, Ahmad Samiei
Gene expression represents a fundamental interface between genes and environment in the development and ongoing plasticity of the human organism. Individual differences in gene exp…