17 citations · 27 across the 6 of their papers we have counts for
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q-bio.BM2023★ 3 cited
Delete: Deep Lead Optimization Enveloped in Protein Pocket through Unified Deleting Strategies and a Structure-aware Network
Haotian Zhang, Huifeng Zhao, Xujun Zhang +10
Drug discovery is a highly complicated process, and it is unfeasible to fully commit it to the recently developed molecular generation methods. Deep learning-based lead optimizatio…
q-bio.BM2023
Highly accurate and efficient deep learning paradigm for full-atom protein loop modeling with KarmaLoop
Tianyue Wang, Xujun Zhang, Odin Zhang +5
Protein loop modeling is the most challenging yet highly non-trivial task in protein structure prediction. Despite recent progress, existing methods including knowledge-based, ab i…