2 papers
physics.chem-ph2026
Rachel: A general-purpose language model directs and revises retrosynthetic routes
Qisheng Li, Shunchao Jiang, Chen Qi +3
Retrosynthetic planning advances through decisions that reshape the remaining chemical problem: a locally plausible disconnection can leave precursors whose chemoselectivity constr…
cs.AI2025
Boosting In-Silicon Directed Evolution with Fine-Tuned Protein Language Model and Tree Search
Yaodong Yang, Yang Wang, Jinpeng Li +4
Protein evolution through amino acid mutations is a cornerstone of life sciences. Recent advances in protein language models have shown rich evolutionary patterns, offering unprece…