195 citations · 399 across the 8 of their papers we have counts for
3 papers · 1 filter
Beyond p-values: a phase II dual-criterion design with statistical significance and clinical relevance
Satrajit Roychoudhury, Nicolas Scheuer, Beat Neuenschwander
Background: Well-designed phase II trials must have acceptable error rates relative to a pre-specified success criterion, usually a statistically significant p-value. Such standard…
Bayesian leveraging of historical control data for a clinical trial with time-to-event endpoint
Satrajit Roychoudhury, Beat Neuenschwander
The recent 21st Century Cures Act propagates innovations to accelerate the discovery, development, and delivery of 21st century cures. It includes the broader application of Bayesi…
Predictively Consistent Prior Effective Sample Sizes
Beat Neuenschwander, Sebastian Weber, Heinz Schmidli +1
Determining the sample size of an experiment can be challenging, even more so when incorporating external information via a prior distribution. Such information is increasingly use…