4 papers · 1 filter
Probing the Mechanisms of Fibril Formation Using Lattice Models
Mai Suan Li, D. K. Klimov, J. E. Straub +1
Using exhaustive Monte Carlo simulations we study the kinetics and mechanism of fibril formation using lattice models as a function of temperature and the number of chains. While t…
Finite size effects on calorimetric cooperativity of two-state proteins
Mai Suan Li, D. K. Klimov, D. Thirumalai
Finite size effects on the calorimetric cooperatity of the folding-unfolding transition in two-state proteins are considered using the Go lattice models with and without side chain…
Finite size effects on thermal denaturation of globular proteins
Mai Suan Li, D. K. Klimov, D. Thirumalai
Finite size effects on the cooperative thermal denaturation of proteins are considered. A dimensionless measure of cooperativity, Omega, scales as N^zeta, where N is the number of…
Thermal denaturation and folding rates of single domain proteins: size matters
Mai Suan Li, D. K. Klimov, D. Thirumalai
We analyze the dependence of thermal denaturation transition and folding rates of globular proteins on the number of amino acid residues, N. Using lattice Go models we show that De…