10 papers
Femtosecond-to-millisecond holographic imaging of laser ablation dynamics
Shotaro Kawano, Keiichiro Toda, Miu Tamamitsu +3
Femtosecond laser ablation redistributes optically deposited energy across electronic, structural, mechanical, and thermal degrees of freedom over timescales from femtoseconds to m…
Pulse-to-pulse spectral phase characterization of mid-infrared pulses at megahertz rates
Zhihao Deng, Zicong Xu, Kazuki Hashimoto +3
Pulse-resolved spectral phase measurement of mid-infrared (MIR) pulses is essential for many applications, from precise waveform control to ultrafast quantum optics. However, conve…
A unified framework for sensitivity comparison across stimulated Raman, stimulated Raman photothermal, and mid-infrared photothermal microscopy
Keiichiro Toda, Takuro Ideguchi
Label-free vibrational microscopy based on Raman scattering and mid-infrared (MIR) absorption has advanced biological imaging through the development of diverse high-sensitivity mo…
Mid-infrared photothermal imaging flow cytometry
Yusei Sugawara, Keiichiro Toda, Genki Ishigane +2
Imaging flow cytometry (IFC) enables high-throughput single-cell analysis but largely relies on fluorescence labeling to obtain molecular specificity. Label-free vibrational imagin…
Label-free mid-infrared photothermal microscopy revisits intracellular thermal dynamics: what do fluorescent nanothermometers measure?
Keiichiro Toda, Masaharu Takarada, Genki Ishigane +4
Fluorescent nanothermometry has revealed pronounced intracellular temperature heterogeneity, establishing the field of single-cell thermal biology. However, these observations have…
Video-rate volumetric chemical imaging via mid-infrared photothermal optical diffraction tomography
Masato Fukushima, Keiichiro Toda, Yusei Sugawara +2
Label-free vibrational microscopy provides chemically specific access to cellular structure, yet quantitative volumetric chemical dynamics in living cells remain largely inaccessib…