23 citations · 60 across the 6 of their papers we have counts for
6 papers
Sensitivity of Phage Lambda upon Variations of the Gibbs Free Energy
Audun Bakk, Ralf Metzler, Kim Sneppen
We investigate the sensitivity of production rates (activities) of the regulatory proteins CI (repressor) and Cro at the right operator (O_R}) of bacteriophage lambda. The DNA bind…
Specific Heat upon Aqueous Unfolding of the Protein Interior: A Theoretical Approach
Audun Bakk, Johan S. Hoye, Alex Hansen
We study theoretically the thermodynamics, over a broad temperature range (5 C to 125 C), related to hydrated water upon protein unfolding. The hydration effect is modeled as inter…
Heat Capacity of Protein Folding
Audun Bakk, Johan S. Hoye, Alex Hansen
We construct a Hamiltonian for a single domain protein where the contact enthalpy and the chain entropy decrease linearly with the number of native contacts. The hydration effect u…
A protein model exhibiting three folding transitions
Audun Bakk, Alex Hansen, Kim Sneppen
We explain the physical basis of a model for small globular proteins with water interactions. The water is supposed to access the protein interior in an "all-or-none" manner during…
Thermodynamical implications of a protein model with water interactions
Audun Bakk, Johan S. Hoye, Alex Hansen +1
We refine a protein model that reproduces fundamental aspects of protein thermodynamics. The model exhibits two transitions, hot and cold unfolding. The number of relevant paramete…
Pathways in Two-State Protein Folding
Audun Bakk, Johan S. Hoye, Alex Hansen +2
The thermodynamics of proteins indicate that folding/unfolding takes place either through stable intermediates or through a two-state process without intermediates. The rather shor…