activity
20172026
most citedActive phase separation in mixtures of chemically interacting particles

194 citations · 1.1k across the 37 of their papers we have counts for

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physics.bio-ph2025

Spatial self-organization of enzymes in complex reaction networks

Vincent Ouazan-Reboul, Ramin Golestanian, Jaime Agudo-Canalejo

Living systems contain intricate biochemical networks whose structure is closely related to their function and allows them to exhibit robust behavior in the presence of external st…

physics.bio-ph2025

Topological edge currents promote exploratory search in microtubule dynamic instability

Chongbin Zheng, Jaime Agudo-Canalejo, Jonathon Howard +1

Microtubules capture chromosomes during mitosis by stochastically switching between growth and shrinkage at catastrophe events. They display strikingly rich biochemistry and dynami…

physics.bio-ph2025

Nonequilibrium protein complexes as molecular automata

Jan Kocka, Kabir Husain, Jaime Agudo-Canalejo

Biology stores information and computes at the molecular scale, yet the ways in which it does so are often distinct from human-engineered computers. Mapping biological computation…

physics.bio-ph2022

Catalysis-Induced Phase Separation and Autoregulation of Enzymatic Activity

Matthew W. Cotton, Ramin Golestanian, Jaime Agudo-Canalejo

We present a thermodynamically consistent model describing the dynamics of a multi-component mixture where one enzyme component catalyzes a reaction between other components. We fi…

physics.bio-ph2021★ 3 cited

Comment on "Relative Diffusivities of Bound and Unbound Protein Can Control Chemotactic Directionality''

Jaime Agudo-Canalejo, Pierre Illien, Ramin Golestanian

This is a comment on a recently published paper in Langmuir: Mandal, N. S.; Sen, A. Relative Diffusivities of Bound and Unbound Protein Can Control Chemotactic Directionality. Lang…

physics.bio-ph2021★ 81 cited

Enhanced diffusion and chemotaxis at the nanoscale

Jaime Agudo-Canalejo, Tunrayo Adeleke-Larodo, Pierre Illien +1

Enzymes have been recently proposed to have mechanical activity associated with their chemical activity. In a number of recent studies, it has been reported that enzymes undergo en…

physics.bio-ph2021★ 113 cited

Phoresis and Enhanced Diffusion Compete in Enzyme Chemotaxis

Jaime Agudo-Canalejo, Pierre Illien, Ramin Golestanian

Chemotaxis of enzymes in response to gradients in the concentration of their substrate has been widely reported in recent experiments, but a basic understanding of the process is s…

physics.bio-ph2017★ 13 cited

Pattern formation by curvature-inducing proteins on spherical membranes

Jaime Agudo-Canalejo, Ramin Golestanian

Spatial organisation is a hallmark of all living cells, and recreating it in model systems is a necessary step in the creation of synthetic cells. It is therefore of both fundament…