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Coordinated Slowing of Metabolism in Enteric Bacteria under Nitrogen Limitation: A Perspective
Ned S. Wingreen, Sydney Kustu
It is natural to ask how bacteria coordinate metabolism when depletion of an essential nutrient limits their growth, and they must slow their entire rate of biosynthesis. A major n…
Identifying Proteins of High Designability via Surface-Exposure Patterns
Eldon G. Emberly, Jonathan Miller, Chen Zeng +2
Using an off-lattice model, we fully enumerate folded conformations of polypeptide chains of up to N = 19 monomers. Structures are found to differ markedly in designability, define…
Emergence of highly-designable protein-backbone conformations in an off-lattice model
J. Miller, C. Zeng, N. S. Wingreen +1
Despite the variety of protein sizes, shapes, and backbone configurations found in nature, the design of novel protein folds remains an open problem. Within simple lattice models i…
Fast Tree Search for Enumeration of a Lattice Model of Protein Folding
Henry Cejtin, Jan Edler, Allan Gottlieb +5
Using a fast tree-searching algorithm and a Pentium cluster, we enumerated all the sequences and compact conformations (structures) for a protein folding model on a cubic lattice o…
Temperature Dependent Suppression of Conductance in Quantum Wires: Anomalous Activation Energy from Pinning of the Band Edge
Kenji Hirose, Ned S. Wingreen
For unpolarized electrons in a clean quantum wire, density functional theory reveals a thermally activated suppression of conductance. The activation temperature T_A grows slowly (…