8 citations · 8 across the 4 of their papers we have counts for
10 papers
Finding regulatory modules through large-scale gene-expression data analysis
Morten Kloster, Chao Tang, Ned Wingreen
The use of gene microchips has enabled a rapid accumulation of gene-expression data. One of the major challenges of analyzing this data is the diversity, in both size and signal st…
Flexibility of beta-sheets: Principal-component analysis of database protein structures
Eldon G. Emberly, Ranjan Mukhopadhyay, Chao Tang +1
Protein folds are built primarily from the packing together of two types of structures: alpha-helices and beta-sheets. Neither structure is rigid, and the flexibility of helices an…
Designability and Thermal Stability of Protein Structures
Ned Wingreen, Hao Li, Chao Tang
Only about 1,000 qualitatively different protein folds are believed to exist in nature. Here, we review theoretical studies which suggest that some folds are intrinsically more des…
Flexibility of -helices: Results of a statistical analysis of database protein structures
Eldon G. Emberly, Ranjan Mukhopadhyay, Ned S. Wingreen +1
-helices stand out as common and relatively invariant secondary structural elements of proteins. However, -helices are not rigid bodies and their deformations can be signific…
The Designability of Protein Structures: A Lattice-Model Study using the Miyazawa-Jernigan Matrix
Hao Li, Chao Tang, Ned Wingreen
We study the designability of all compact 3x3x3 and 6x6 lattice-protein structures using the Miyazawa-Jernigan (MJ) matrix. The designability of a structure is the number of sequen…
Coordinated Slowing of Metabolism in Enteric Bacteria under Nitrogen Limitation: A Perspective
Ned S. Wingreen, Sydney Kustu
It is natural to ask how bacteria coordinate metabolism when depletion of an essential nutrient limits their growth, and they must slow their entire rate of biosynthesis. A major n…