1.9k citations · 9.3k across the 81 of their papers we have counts for
82 papers
Propelling catalytic structures using active phase separation
Benjamin Sorkin, Ned S. Wingreen
Living systems routinely consume energy to achieve motility, often using intricate biomolecular machinery. In this work, we show that active droplets can sustain indefinite self-pr…
Roadmap for Condensates in Cell Biology
Dilimulati Aierken, Sebastian Aland, Stefano Bo +38
Biomolecular condensates govern essential cellular processes yet elude description by traditional equilibrium models. This roadmap, distilled from structured discussions at a works…
Morphogenesis of bacterial colonies in liquid crystalline environments
Sebastian Gonzalez La Corte, Thomas G. J. Chandler, Saverio E. Spagnolie +2
Natural bacterial habitats are often complex fluids with viscoelastic and anisotropic responses to stress; for example, they can take the form of liquid crystals (LCs), with elonga…
Accelerated Ostwald ripening by chemical activity
Benjamin Sorkin, Ned S. Wingreen
Phase separation of biomolecular condensates promotes membrane-free compartmentalization in cells. The dynamics of these biocondensates is routinely regulated by energy-consuming p…
Data-driven Discovery of Biophysical T Cell Receptor Co-specificity Rules
Andrew G. T. Pyo, Yuta Nagano, Martina Milighetti +5
The biophysical interactions between the T cell receptor (TCR) and its ligands determine the specificity of the cellular immune response. However, the immense diversity of receptor…
Local polar order controls mechanical stress and triggers layer formation in developing Myxococcus xanthus colonies
Endao Han, Chenyi Fei, Ricard Alert +4
Colonies of the social bacterium Myxococcus xanthus go through a morphological transition from a thin colony of cells to three-dimensional droplet-like fruiting bodies as a strateg…