89 citations · 139 across the 19 of their papers we have counts for
9 papers · 1 filter
Spike-timing-dependent plasticity and random inputs shape interspike interval regularity of model STN neurons
Thoa Thieu, Roderick Melnik
Neuronal oscillations are closely related to the symptoms of Parkinson's disease (PD). In this study, we explore how random fluctuations (or "stochastic inputs") affect these oscil…
Complex non-Markovian dynamics and the dual role of astrocytes in Alzheimer's disease development and propagation
Swadesh Pal, Roderick Melnik
Alzheimer's disease (AD) is a common neurodegenerative disorder nowadays. Amyloid-beta (A) and tau proteins are among the main contributors to the development or propagation of…
Effects of random inputs and short-term synaptic plasticity in a LIF conductance model for working memory applications
Thi Kim Thoa Thieu, Roderick Melnik
Working memory (WM) has been intensively used to enable the temporary storing of information for processing purposes, playing an important role in the execution of various cognitiv…
Effects of noise on leaky integrate-and-fire neuron models for neuromorphic computing applications
Thi Kim Thoa Thieu, Roderick Melnik
Artificial neural networks (ANNs) have been extensively used for the description of problems arising from biological systems and for constructing neuromorphic computing models. The…
Nonlocal Models in the Analysis of Brain Neurodegenerative Protein Dynamics with Application to Alzheimer's Disease
Swadesh Pal, Roderick Melnik
It is well known that today nearly one in six of the world's population has to deal with neurodegenerative disorders. While a number of medical devices have been developed for the…
Deep brain stimulation with a computational model for the cortex-thalamus-basal-ganglia system and network dynamics of neurological disorders
Hina Shaheen, Roderick Melnik
Deep brain stimulation (DBS) can alleviate the movement disorders like Parkinson's disease (PD). Indeed, it is known that aberrant beta (13-30Hz)oscillations and the loss of dopami…
Coupled effects of channels and synaptic dynamics in stochastic modelling of healthy and Parkinson's-disease-affected brains
Thi Kim Thoa Thieu, Roderick Melnik
Our brain is a complex information processing network in which the nervous system receives information from the environment to quickly react to incoming events or learns from exper…
The topology of higher-order complexes associated with brain-function hubs in human connectomes
Miroslav Andjelkovic, Bosiljka Tadic, Roderick Melnik
Higher-order connectivity in complex systems described by simplexes of different orders provides a geometry for simplex-based dynamical variables and interactions. Simplicial compl…
Functional Geometry of Human Connectome and Robustness of Gender Differences
Bosiljka Tadic, Miroslav Andjelkovic, Roderick Melnik
Mapping the brain imaging data to networks, where each node represents a specific area of the brain, has enabled an objective graph-theoretic analysis of human connectome. However,…