activity
20232026
most citedBayesian inference and role of astrocytes in amyloid-beta dynamics with modelling of Alzheimer's disease using clinical data

2 citations · 5 across the 13 of their papers we have counts for

collaborators

13 papers

cs.LG2026

Machine Learning for Complex Systems Dynamics: Detecting Bifurcations in Dynamical Systems with Deep Neural Networks

Swadesh Pal, Roderick Melnik

Critical transitions are the abrupt shifts between qualitatively different states of a system, and they are crucial to understanding tipping points in complex dynamical systems acr…

q-bio.NC2025

Adaptive modelling of anti-tau treatments for neurodegenerative disorders based on the Bayesian approach with physics-informed neural networks

Swadesh Pal, Roderick Melnik

Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by the accumulation of amyloid-beta (A) and phosphorylated tau (p-tau) proteins, leading to cognit…

q-bio.PE2025

Innate behavioural mechanisms and defensive traits in ecological models of predator-prey types

Sangeeta Saha, Swadesh Pal, Roderick Melnik

There are various examples of phenotypic plasticity in ecosystems that serve as the basis for a wide range of inducible defences against predation. These strategies include camoufl…

q-bio.PE2024

The role of inducible defence in ecological models: Effects of nonlocal intraspecific competitions

Sangeeta Saha, Swadesh Pal, Roderick Melnik

Phenotypic plasticity is a key factor in driving the evolution of species in the predator-prey interaction. The natural environment is replete with phenotypic plasticity, which is…

q-bio.NC2024★ 1 cited

Brain Network Dynamics and Multiscale Modelling of Neurodegenerative Disorders: A Review

Hina Shaheen, Roderick Melnik

It is essential to understand the complex structure of the human brain to develop new treatment approaches for neurodegenerative disorders (NDDs). This review paper comprehensively…

q-bio.NC2024

Bayesian Approaches for Revealing Complex Neural Network Dynamics in Parkinson's Disease

Hina Shaheen, Roderick Melnik

Parkinson's disease (PD) belongs to the class of neurodegenerative disorders that affect the central nervous system. It is usually defined as the gradual loss of dopaminergic neuro…

math.DS2024

Nonlocal cooperative behaviour, psychological effects, and collective decision-making: an exemplification with predator-prey models

Sangeeta Saha, Swadesh Pal, Roderick Melnik

In bio-social models, cooperative behaviour has evolved as an adaptive strategy, playing multi-functional roles. One of such roles in populations is to increase the success of surv…

q-bio.QM2024★ 2 cited

Nonlocal Models in Biology and Life Sciences: Sources, Developments, and Applications

Swadesh Pal, Roderick Melnik

Nonlocality is important in realistic mathematical models of physical and biological systems when local models fail to capture the essential dynamics and interactions that occur ov…

q-bio.PE2023

The Role of Soil Surface in a Sustainable Semiarid Ecosystem

Swadesh Pal, Malay Banerjee, Roderick Melnik

Patterns in a semiarid ecosystem are important because they directly and indirectly affect ecological processes, biodiversity, and ecosystem resilience. Understanding the causes an…

q-bio.PE2023

Analysis of the impact of fear in the presence of additional food and prey refuge with nonlocal predator-prey models

Sangeeta Saha, Swadesh Pal, Roderick Melnik

There are many positive and negative factors present in the predator-prey interaction which affect the net growth of the species. Fear of predation is one such factor that creates…

physics.soc-ph2023

Social human collective decision-making and its applications with brain network models

Thoa Thieu, Roderick Melnik

In this chapter, we consider probabilistic drift-diffusion models and Bayesian inference frameworks to address this issue, assisting better social human decision-making. We provide…

q-bio.NC2023★ 2 cited

Bayesian inference and role of astrocytes in amyloid-beta dynamics with modelling of Alzheimer's disease using clinical data

Hina Shaheen, Roderick Melnik, The Alzheimer's Disease Neuroimaging Initiative

Alzheimer's disease (AD) is a prominent, worldwide, age-related neurodegenerative disease that currently has no systemic treatment. Strong evidence suggests that permeable amyloid-…

q-bio.NC2023

Data-driven Stochastic Model for Quantifying the Interplay Between Amyloid-beta and Calcium Levels in Alzheimer's Disease

Hina Shaheen, Roderick Melnik, Sundeep Singh

The abnormal aggregation of extracellular amyloid- (Aβ) in senile plaques resulting in calcium (Ca^{+2}) dyshomeostasis is one of the primary symptoms of Alzheimer's disease (AD…