16 citations · 72 across the 18 of their papers we have counts for
Showing 2023Show all
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stat.AP2023★ 2 cited
A Multi-Arm Two-Stage (MATS) Design for Proof-of-Concept and Dose Optimization in Early-Phase Oncology Trials
Zhenghao Jiang, Gu Mi, Ji Lin +2
The Project Optimus initiative by the FDA's Oncology Center of Excellence is widely viewed as a groundbreaking effort to change the of conventional dose-findi…
stat.AP2023★ 9 cited
The Backfill i3+3 Design for Dose-Finding Trials in Oncology
Jiaxin Liu, Shijie Yuan, B. Nebiyou Bekele +1
We consider a formal statistical design that allows simultaneous enrollment of a main cohort and a backfill cohort of patients in a dose-finding trial. The goal is to accumulate mo…